学术报告（一）

报告题目：设计与合成小分子探针用于活体细胞成像
报  告 人：杨俊博士（加州大学圣地亚哥分校）
时       间：2012年12月14日（本周五）上午9:00
地　　点：创新药物研究中心205会议室

报告人简介：
Education and Research Backgound
Postdoctoral Fellow, University of California, San Diego
N. K. Devaraj Lab  
· Developed a metal catalyzed method to one-pot synthesis of 1,2,4,5-tetrazine from
unactive nitrile  
· Design and synthesis of new cyclopropene mini-tag for live cell image.
2011, Nov. – Present
Research Associate, The Scripps Research Institute
Ed. Roberts Lab 2009, May – 2011, Nov.
· Total synthesis of epoxyresibufogenin as antagonist of interleukin-6 receptor.
· Successfully synthesis of 20 triazine compounds as antagonist of prokineticin receptor.
· Successfully design and synthesize the first positive allosteric modulator of oxytocin  receptor.
· Design and synthesis of new antagonist of neuropeptide Y receptor.
K. C. Nicolaou Lab 2008, Sep. – 2009, May
· Total synthesis of brasiliensophyllic acid A.
Ph.D in Medicinal Chemistry Sichuan University, Yong Qin Lab – Chengdu,China
· Successfully developed an intramolecular cyclopropanation methodology to
assembling pentacyclic skeleton of communesin and finished the first total synthesis
of (±)-communesin F 2003, Sep. – 2008, July
Master in Pesticide Chemistry Guizhou University – Guiyang, China
· Synthesis of a series of new nereistoxin derivates and investigation of its
reaction mechanism 2000, Sep – 2003, July
Bachelor in Applied chemistry Guzhou University, China 1994, Sep – 1998, July


学术报告（二）

报告题目：Total Synthesis of (±)-Minfiensine,(±)-Vincorine and (±)- Harringtonolide
报  告 人：张敏博士（美国Wisconsin大学Madison分校）
时       间：2012年12月14日（本周五）上午10:00
地       点：创新药物研究中心205会议室

报告人简介：
Education Background
September, 2009-present
School of Pharmacy, University of Wisconsin-Madison,
Postdoctoral Fellow in Pharmaceutical Sciences. Advisor: Prof. Weiping Tang.

September, 2003-June, 2009
West China School of Pharmacy, Sichuan University,
Ph. D. in Medicinal Chemistry. Advisor: Prof. Yong Qin.

September, 1999-June, 2003
West China School of Pharmacy, Sichuan University, B. S. in Pharmacy.
Academic Research Experience

2009- present Total Synthesis of Harringtonolide, Fortunolide A and Welwitindolinones.
2007-2009 Doctoral Graduate Research Program: Total Synthesis of the Akuammiline Alkaloid Vincorine.
2003-2006 Doctoral Graduate Research Program: Assembly of Vincorine Type Alkaloid Skeleton by Cyclopropanation and Total Synthesis of Minfiensine.